Full Set In Stock | Adrenaline Impurities Now Shining Bright!

Adrenaline is an agonist for α and β receptors. It acts on α1 receptors in vascular smooth muscle, causing vasoconstriction, while also stimulating β2 receptors to induce vasodilation (primarily in skeletal muscle, liver, and coronary vessels). Additionally, it affects β receptors in the myocardium, sinoatrial node, and conduction system, enhancing myocardial contraction, increasing heart rate, accelerating conduction, and improving cardiac output.

As a vital hormone in the human body, Adrenaline has become an indispensable drug in clinical emergency care. It is recommended as a core medication in cardiopulmonary resuscitation (CPR) by international CPR guidelines. Moreover, in the treatment of anaphylactic shock, Adrenaline rapidly activates both α and β receptors. This not only reduces exudation and alleviates laryngeal edema but also elevates blood pressure, strengthens cardiac function, and relieves bronchial smooth muscle spasms.

Adrenaline is chemically unstable and prone to oxidation, especially in neutral or alkaline solutions, leading to loss of efficacy. Intermediate compounds, degradation products, and process-related impurities generated during its synthesis may significantly impact the drug’s safety and effectiveness. As a critical emergency medication, the quality of Adrenaline is directly linked to patient safety. Excessive impurity levels may reduce efficacy, increase adverse reactions, and pose additional safety risks.

Stringent control of Adrenaline impurities is essential to ensure drug safety and efficacy. SZEB  specializes in supplying Adrenaline impurity reference standards, including the N-NitrosoAdrenaline series and Adrenaline EP impurity series, to meet diverse experimental needs. These products support pharmaceutical companies in the research, production, and quality control of Adrenaline. For more details, visit our official website: www.ex-biotech.com , or e-mail:sales@ex-biotech.cn .